Targeted Therapy
Drugs matched to the specific genetic change driving a particular tumour — often tablets taken at home. When the biopsy shows the right target, these are some of the most effective medicines in oncology.
What "targeted" actually means
Some cancers are driven by one identifiable fault — a mutated gene acting like a stuck accelerator. Targeted drugs block that specific fault. Where chemotherapy attacks all fast-dividing cells, a targeted drug switches off the one signal this tumour depends on, which is why the right drug in the right patient can shrink disease dramatically with comparatively modest side effects.
The catch is in the word "right": the drug only works if your tumour carries its target. Testing the biopsy — molecular or biomarker testing — is what separates precision medicine from expensive guessing.
Where it changes outcomes
- 01Lung cancerEGFR, ALK and other mutations — tablets that outperform chemotherapy in mutation-positive disease
- 02Breast cancerHER2-positive disease transformed by anti-HER2 drugs; hormone-driven disease managed for years with endocrine and CDK-inhibitor tablets
- 03GI and other cancersTargets in colorectal, stomach and GIST tumours guide both drug choice and drugs to avoid
- 04Kidney and gynaecological cancersAnti-angiogenic and PARP-inhibitor strategies in selected patients
What treatment is like
Many targeted drugs are once- or twice-daily tablets, taken at home with clinic reviews and periodic scans — treatment woven into life rather than life around treatment. Side effects are real but drug-specific — skin changes, diarrhoea, blood-pressure effects among them — and are managed by adjusting dose rather than abandoning the drug. Over time some tumours evolve resistance; that is expected, watched for on scans, and met with a planned next line rather than surprise.
Common questions
How do you know if a targeted drug will work for me?
Are tablets really as serious a treatment as a drip?
What does molecular testing cost, and is it covered?
What happens when the drug stops working?
Cancers we treat with targeted therapy
- 01Chest & Lung Cancer →Lung, mediastinum and chest wall tumours
- 02Breast Cancer →Screening, breast-conserving surgery, reconstruction
- 03Gastrointestinal Cancer →Stomach, colon, rectum, oesophagus, liver and pancreas
- 04Urological Cancer →Kidney, bladder, prostate
- 05Gynaecological Cancer →Cervix, ovary, uterus — including robotic approaches
Send us the biopsy report. We will tell you where you stand.
A second opinion costs you nothing and often changes the plan. Share your reports on WhatsApp and a surgical oncologist will review them before your first visit.